How is lidocaine administered?

• A. Intradermally
• B. Intravenously
• C. Subcutaneously
• D. Orally

Answer: (B)

Lidocaine’s systemic effects, such as treating certain heart rhythm problems, require rapid and controllable entry into the bloodstream. Delivering it intravenously achieves immediate, predictable plasma levels and quick distribution to cardiac tissue, which is essential for the intended antiarrhythmic action. Oral administration is impractical here because lidocaine is poorly absorbed and undergoes extensive first-pass metabolism, leading to unreliable and delayed effects. Local anesthesia routes like intradermal or subcutaneous deliver the drug to nearby tissues rather than providing the rapid systemic effect needed for heart rhythm control. Therefore, intravenous administration is the best choice when lidocaine is used for systemic effects.