Germicide rebound during dialysis is most directly related to which step of the dialysis setup?

• A. Adequate dialyzer priming
• B. Inadequate dialyzer priming
• C. Dialysate temperature
• D. Blood pump troubleshooting

Answer: (B)

Germicide rebound occurs when residual disinfectant used to sanitize the dialyzer and circuit remains in the system and then enters the patient’s bloodstream once dialysis starts. The most direct factor is how well the dialyzer and circuit are primed and flushed after disinfection. If priming is inadequate, disinfectant residues can linger and rebound into the blood during treatment. Dialysate temperature and blood pump troubleshooting don’t address these chemical residues, so they’re not the direct cause.