A patient with diabetes should be observed for signs of low blood sugar, which include:

• A. Anxiety and confusion
• B. Sweating and tremor
• C. Nausea
• D. Sleepiness

Answer: (A)

Low blood sugar triggers both a quick autonomic response and brain glucose deprivation. Anxiety reflects the adrenergic warning signal the body releases early on, while confusion shows the brain isn’t getting enough glucose and is starting to malfunction. Together, these signs cover both the sympathetic response and the cognitive impact of hypoglycemia, making this pairing the most representative combination. Sweating and tremor are common early signs but don’t capture brain involvement as clearly, nausea is less specific, and sleepiness tends to appear later as hypoglycemia worsens. If these signs are observed, check the blood glucose and treat promptly with fast-acting carbohydrates if hypoglycemia is confirmed.